REVIEWCell membrane-derived vesicles for delivery of therapeutic agents
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Graphical abstract
Cell membrane-derived nanovesicles contain the intrinsic functionalities of their parent cells, and have potential as new molecular delivery systems.
KEY WORDS
Cell membrane-derived vesicles
Membrane engineering
Drug-delivery systems
Blood cells
Immune cells
Stem cells
Cancer cells
Manufacturing
Abbreviations
CAR-T
chimeric antigen receptor-engineered T cell
CRISPR
clustered regularly interspaced short palindromic repeats
CXCR4
C-X-C chemokine receptor type 4
DC
dendritic cell
NF-κB
nuclear factor kappa B
NIR
near infrared
PEG
polyethylene glycol
PLGA
poly(lactic-co-glycolic acid)
RBC
red blood cell
TCR
T-cell receptor
TRAIL
tumor necrosis factor-related apoptosis-inducing ligand
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Peer review under responsibility of Chinese Pharmaceutical Association and Institute of Materia Medica, Chinese Academy of Medical Sciences.
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These authors made equal contributions to this work.
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